PUBLICATIONS

PEER REVIEWED PAPERS:

  1. Mashiah, L. Beck, E., Shani Levi, C. and Lesmes, U. (2025). Sex-Based Differences in In Vitro Digestibility of Milk and Oat Drink, and Powder Counterparts, Food Research International, 214, 116610.
  2. Lifshitz, Y, Paz. S., Saban, R., Zuker, I., Shmuely, H., Gorshkov, K., Meetro, J.,m Tafazoli, S., Vo, T., Amiram, G., Shani Levi, C., Lesmes, U. and Samish, I. (2025). Safety evaluation of Serendipity Berry Sweet Protein from Komagataella phaffii, Journal of Applied Toxicology, Accepted In Press. DOI: 10.1002/jat.4781.
  3. Mashiah, L., Medini, O., Araiza Calahorra, A., Skaret, J., Shani Levi, C., Egger, L., Portmann, R., Varela, P., Sarkar, A. and Lesmes, U. (2025). Tailored Co-Extruded Cereals for Seniors: Fabrication, Palatability, and in vitro Digestibility, Food Science and Human Wellness, 15.
  4. Perez, M., Shani Levi, C. and Lesmes, U. (2025). Sex-Based Differences in the In Vitro Digestibility of MCT Emulsions Stabilized by Various Emulsifiers, Foods, 14(1), 131.
  5. Yaskin Harush, M., Shani Levi, C. and Lesmes, U. (2025). Potential of process-induced modification of potato starch to modulate starch digestibility and levels of Resistant starch type III, Foods, 14(5), 880.
  6. Delmar, K., Kablan, R., Amiram, G., Shani Levi, C., Lesmes, U. and Bianco-Peled, H. (2025). The effect of Alginate and k-Carrageenan on the stability of Pickering emulsions stabilized by Shellac-based Nanoparticles, Polysaccharides, 6, 35.
  7. Prinz Setter, O., Gilboa, A., Shalash, G., Refael, G., Tarazi-riess, H., Shani-Levi, C., Lesmes, U. and Segal, E., (2024). Introducing HaNTS – Halloysite Nanotubes Targeting System for the Selective Delivery of Antibiotics to Specific Bacteria. Advanced Functional Materials,2315923.
  8. Refael, G., Engelberg, Y., Romano, A., Barnea, E., Shani Levi, C., Turjeman, S., Landau, M., Koren, O. and Lesmes, U., (2024). Milk and egg-derived amyloids attenuate digestive proteolysis and affect the trajectory of the gut microbiota. Food Hydrocolloids, 151, 109820
  9. Tarazi-Riess, H., Shani-Levi, C. and Lesmes, U.(2024). Heat-moisture and acid treatments can increase levels of Resistant Starch in Arrow root starch without adversely affecting its prebiotic activity in human colon microbiota. Food and Function, 15, 5813-5824.
  10. Yu, P., Zeng, Y., Li, C., Qiu, B., Shi, Y., He, Q., Lesmes, U. and Achmon, Y. (2024), Quality changes during storage and sex-based in vitro bioaccessibility of Citri Reticulatae Pericarpium (pericarps of Citrus reticulata ‘Chachi’). Foods, 13(22), 3671.
  11. Menard, O., Lesmes**, U., Shani-Levi, C., Araiza Calahorra, A., Lavoisier, A., Morzel, M., Rieder, A., Feron, G., Nebbia, S., Mashiah, L., Andres, A., Bornhorst, G., Carrière, F., Egger, L., Gwala, G., Heredia, A., Kirkhus, B., Macierzanka , A., Portmann, A., Recio, I., Santé-Lhoutellier, V., Tournier, C., Sarkar, A., Brodkorb, A., Mackie, A. and Dupont, D. (2023). Static in vitro digestion model adapted to the general older adults: an INFOGEST international consensus. Food and Function, 14, 10, 4569-4582. (**Co-First Author).
  12. Romano, A. Engelberg, Y., Landau, M. and Lesmes, U. (2023). Amyloid fibrils for intestinal delivery: Formation, physiochemical characterization, and digestive fate of capsaicin-loaded alpha-lactalbumin fibrils. Food Hydrocolloids, 136, A, 108248.
  13. David-Birman, T., Romano, A., Aga, A., Pascoviche, D., Davidovich-Pinhas, M. and Lesmes, U. (2022). Impact of silkworm pupae (Bombyx mori) powder on cream foaming, ice cream properties and palatability, Innovative Food Science and emerging Technologies, 75, 102874.
  14. Romano, A., Shani Levi, C. and Lesmes, U. (2022). Bovine alpha-lactalbumin particulates for controlled delivery: Impact of dietary fibers on stability, digestibility, and gastro-intestinal release of capsaicin. Food Hydrocolloids, 128, 107536.
  15. Lajterer, C., Shani Levi, C. and Lesmes, U. (2022). An in vitro digestion model accounting for sex differences in gastro-intestinal functions and its application to study differential protein digestibility. Food Hydrocolloids, 132, 107850.
  16. Tarazi Riess, H., Shani Levi, C. and Lesmes, U. (2022). Inclusion of phenolic bioactives in high amylose corn starch (HACS) for gastro-intestinal delivery. Frontiers in Nutrition, 9.
  17. Refael, G., Tarazi-Riess, H., Shani Levi, C., Magzal, F., Tamir, S., Koren, O. and Lesmes U. (2022). Responses of the human gut microbiota to physiologically digested insect powders or isolated chitin thereof. Future Foods, 6, 100197.
  18. Issaschar Ovdat, S., Shani Levi, C. and Lesmes, U. (2021). Capsaicin stability and bio-accessibility affected by complexation with high-amylose corn starch (HACS). Food & Function, 12, 6992.
  19. Romano, A. Lajterer, C. Shpigelman, A. and Lesmes, U. Bovine alpha-lactalbumin assemblies with capsaicin: Formation, interactions, loading and physiochemical characterization, Food Chemistry, Accepted – In Press.
  20. Nagar, E.E., Berenshtein, L., Katz, I.H., Lesmes, U., Okun, Z. and Shpigelman, A. (2021). The impact of chemical structure on polyphenol bioaccessibility, as a function of processing, cell wall material and pH: A model system. Journal of Food Engineering, 289, 110304.
  21. Ashkar, A., Rosen-Kligvasser , J., Lesmes, U. and Davidovich-Pinhas M., (2020) Controlling lipid intestinal digestibility using various oil structuring mechanisms, Food and Function, 11, 7495.
  22. David, S., Magram Klaiman, M., Shpigelman, A. and Lesmes, U. (2020). Addition of Anionic Polysaccharide Stabilizers Modulates In Vitro Digestive Proteolysis of a Chocolate Milk Drink in Adults and Children. Foods, 9(9), 1253.
  23. Stubler, A.S., Lesmes, U., Juadjur, A., Heinz, V., Rauh, C., Shpigelman, A. and Aganovic, K. Impact of pilot-scale processing (thermal, PEF, HPP) on the stability and bioaccessibility of polyphenols and proteins in mixed protein- and polyphenol-rich juice systems. Innovative Food Science and Emerging Technologies. Accepted – In Press.
  24. David, S., Wojciechowska, A., Portmann, R., Shpigelman, A. and Lesmes, U. (2020).The impact of food-grade carrageenans and consumer age on the in vitro proteolysis of whey proteins, Food Research International, 130, 108964.
  25. Stubler, A.S., Lesmes, U., Heinz, V., Rauh, C., Shpigelman, A. and Aganovic, K.  (2019). Digestibility, antioxidative activity and stability of plant protein‑rich products after processing and formulation with polyphenol‑rich juices: kale and kale–strawberry as a model. European Food Research and Technology, 245, 2499–2514. 
  26. Ashkar, A., Laufer, S., Rosen-Kligwasser, Y., Lesmes, U. and Davidovich-Pinhas, M. (2019). Impact of different oil gelators and oleogelation mechanisms on digestive lipolysis of canola oil oleogels. Food Hydrocolloids, 97, 105218.
  27. David-Birman, T., Moshe, H. and Lesmes, U. (2019) Impact of thermal processing on physicochemical properties of silk moth pupae (Bombyx mori) flour and in-vitro gastrointestinal proteolysis in adults and seniors. Food Research International, 123, 11-19.
  28. Brodkorb, A., Egger, L., Alminger, M., Alvito, P., Ballance, S., Bohn, T., Bourlieu, C., Boutrou, R., Carrière, F., Corredig, M., Dupont, D., Dufour, C., Edwards, C., Golding, M., Karakaya, S., Kirkhus, B., Le Feunteun, S., Lesmes, U., Macierzanka, A., Mackie, A., McClements, D.J., Ménard, O., Minekus, M., Portmann, R., Santos, C.,  Souchon, I., Singh, R.P., Vegarud, G.E., Wickham, M., Weitschies, W. and Recio I., (2019) INFOGEST static in vitro simulation of gastrointestinal food digestion, Nature Protocols, 14, 991-1014.
  29. Meshulam Pascoviche, D., Goldstein, N., Fishman, A. and Lesmes, U. (2019) Impact of fatty acids unsaturation on stability and intestinal lipolysis of bioactive lipid droplets. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 561, 70-78. 
  30. David-Birman, T., Raften, G. and Lesmes, U. (2018). Effects of thermal treatments on the colloidal properties, antioxidant capacity and In-vitro proteolytic degradation of cricket flour. Food Hydrocolloids, 79, 48-54.   
  31. Joubran, Y., Moscovici, A., Portmann, R. and Lesmes, U. (2017). Implications of the Maillard reaction on bovine alpha-lactalbumin properties and proteolytic breakdown during in vitro infant digestion, Food and Function, 8, 2295-2308.
  32. Cohen, Y., Levi, M., Lesmes, U., Margier, M., Reboul, E. and Livney, Y.D. (2017). Re-assembled casein micelles improve in vitro bioavailability of vitamin D in a Caco-2 cell model. Food and Function, 8, 2133 – 2141.
  33. Shani Levi, C., Goldstein, N., Portmann, R. and Lesmes U. (2017). Emulsion and protein degradation in the elderly: Qualitative insights from a study coupling a dynamic in vitro digestion model with proteomic analyses. Food Hydrocolloids, 69, 393-401.
  34. Fahoum, L., Moscovici, A.M., David, S., Shaoul, R., Rozen, G., Meyron-Holtz, E.G. and Lesmes, U. (2017). Digestive fate of dietary carrageenan: Evidence of interference with digestive proteolysis and disruption of gut epithelial function. Molecular Nutrition and Food Research, 61, 3, 1600545.
  35. Egger, L., Ménard, O., Delgado-Andrade, C., Alvito, P., Assunção, R., Balance, S., Barberá, R., Brodkorb, A., Cattenoz, T., Clemente, A., Comi, I., Dupont, D., Garcia-Llatas, G., Jesús Lagarda, M., Le Feunteun, S., JanssenDuijghuijsen, L., Karakaya, S., Lesmes, U.,  Mackie, A.R., Martins, C., Meynier, A., Miralles, B., Murray, B.S., Pihlanto, A., Picariello, G., Santos, C.N., Simsek, S., Recio, I., Rigby, N., Rioux, L.E., Stoffers, H., Tavares, A., Tavares, L., Turgeon, S., Ulleberg, E.K., Vegarud, G.E., Vergères G. and Portmann, R. (2016). The harmonized INFOGEST in vitro digestion method: From knowledge to action. Food Research International, 8, B, 217-225.    
  36. Joubran, Y., Moscovici, A.M. and Lesmes, U. (2015), Antioxidant activity of bovine alpha lactalbumin Maillard products and evaluation of their in vitro gastro-duodenal digestive proteolysis. Food & Function , 6 (4), 1229-1240.    
  37. Isaschar-Ovdat, S., Rosenberg, M., Lesmes, U. and Fishman, A. (2015). Characterization of oil-in-water emulsions stabilized by tyrosinase-crosslinked soy glycinin, Food Hydrocolloids, 43, 493–500.
  38. Shani-Levi, C. and Lesmes, U. (2014). Bi-compartmental elderly or adult dynamic digestion models applied to interrogate protein digestibility, Food and Function, 5, 2402-2409.    
  39. Meshulam, D., Slavuter, J. and Lesmes, U. (2014). Stability of emulsions stabilized by a hydrophobically modified Inulin to bio-relevant conditions of the human gastro-intestine, Food Biophysics, 9, 4, 416-423.     
  40. Moscovici, A.M, Joubran, Y., Mackie, A., Dupont, D. and Lesmes, U. (2014). Impact of the Maillard reaction on the in vitro proteolytic breakdown of bovine lactoferrin in adults and infants, Food and Function, 5 (8), 1898 – 1908.
  41. Minekus, M., Alminger, M., Alvito, P., Ballance, S., Bohn, T., Bourlieu, C., Carrière, F., Boutrou, R., Corredig, M.,  Dupont, D., Dufour, C.,  Egger, C., Golding, M., Karakaya, S., Kirkhus, B., Le Feunteun, S., Lesmes, U., Macierzanka, A., Mackie, A., McClements, D.J., Ménard, O., Recio, I., Santos, C., Singh, P.R., Vegarud, G.E., Wickham, M., Weitschies, W. and Brodkorb, A. (2014). A standardised static in vitro digestion method suitable for food – an international consensus, Food and Function, 5, 1113-1124.
  42. Ruiz-Rodriguez, P.E., Meshulam, D. and Lesmes, U. (2014). Characterization of Pickering O/W emulsions stabilized by silica nanoparticles and their responsiveness to in vitro digestion conditions. Food Biophysics, 9, 4, 406-415.
  43. Pérez, O. E., David-Birman, T., Kesselman, E., Levi-Tal, S., Lesmes, U. (2014). Milk protein–vitamin interactions: Formation of beta-lactoglobulin/folic acid nano-complexes and their impact on in vitro gastro-duodenal proteolysis. Food Hydrocolloids, 38, 40-47.
  44. Meshulam, D., Lesmes, U. (2014). Responsiveness of emulsions stabilized by lactoferrin nano-particles to simulated intestinal conditions. Food & Function, 5, 65-73.
  45. Joubran, Y., Mackie, A., and Lesmes, U. (2013). Impact of the Maillard reaction on the antioxidant capacity of bovine lactoferrin. Food Chemistry, 141(4), 3796-3802.
  46. Shimoni, G., Shani Levi, C., Levi Tal, S. and Lesmes, U. (2013). Emulsions stabilization by lactoferrin nano-particles under in vitro digestion conditions. Food Hydrocolloids, 33(2), 264-272.
  47. Shani-Levi, C., Tal Levi, S. and Lesmes, U. (2013). Comparative performance of milk proteins and their emulsions under dynamic in vitro adult and infant gastric digestion. Food Hydrocolloids, 32(2): 349-357.
  48. David-Birman, T., Mackie, A. and Lesmes, U. (2013). Impact of dietary fibers on the properties and proteolytic digestibility of lactoferrin nano-particles. Food Hydrocolloids, 31(1): 33–41.3.
  49. Tokle, T., Lesmes, U., Decker, E.A. and McClements D.J. (2012). Impact of dietary fiber coatings on behavior of protein-stabilized lipid droplets under simulated gastrointestinal conditions. Food and Function, 3, 58-66.
  50. Lesmes, U. and McClements, D.J. (2012). Controlling Lipid Digestibility: Response of lipid droplets coated by b-lactoglobulin-dextran Maillard conjugates to simulated gastrointestinal conditions. Food Hydrocolloids, 26, 1, 221-230.
  51. Schmelz, T., Lesmes, U., Weiss, J. and McClements, D.J. (2011). Modulation of physicochemical properties of lipid droplets using β-lactoglobulin and/or lactoferrin interfacial coatings, Food Hydrocolloids, 25, 1181-1189.
  52. Tokle, T., Lesmes, U. and McClements D.J. (2010). Impact of electrostatic deposition of anionic polysaccharides on the stability of oil droplets coated by lactoferrin. Journal of Agricultural and Food Chemistry, 58, 17, 9825-9832.
  53. Lesmes, U., Baudot, P. and McClements, D.J. (2010). Impact of interfacial composition on physical stability and in vitro lipase digestibility of triacylglycerol oil droplets coated with lactoferrin and/or caseinate, Journal of Agricultural and Food Chemistry, 58, 13, 7962–7969.
  54. Matalanis, A., Lesmes, U., Decker, E.A. and McClements, D.J. (2010). Fabrication and Characterization of Filled Hydrogel Particles based on Sequential Segregative and Aggregative Biopolymer Phase Separation. Food Hydrocolloids, 24, 689-701.
  55. Peinado, I., Lesmes, U., Andres, A. and McClements, D. J. (2010).  Fabrication and morphological characterization of biopolymer particles formed by electrostatic complexation of heat treated lactoferrin and anionic polysaccharides, Langmuir, 26, 12, 9827–9834.
  56. Lesmes, U., Sandra, S., Decker, E. A. and McClements, D. J. (2009). Impact of surface deposition of lactoferrin on the physical and chemical stability of omega-3 rich oil droplets stabilized by caseinate. Food chemistry, 123, 1, 99-10.
  57. Jones, O. G., Lesmes, U., Decker, E. A., Dubin, P. and McClements, D. J. (2009). Effect of Polysaccharide Charge on Formation and Properties of Biopolymer Nanoparticles Created by Heat Treatment of β-Lactoglobulin-Pectin Complexes. Food Hydrocolloids, 24, 4, 374-383.
  58. Zabar, S., Lesmes, U., Katz, I., Shimoni, E. and Bianco-Peled, H. (2009). Structural characterization of amylose-long chain fatty acid complexes produced via the acidification method. Food hydrocolloids, 24, 4, 347-357.
  59. Zabar, S., Lesmes, U., Katz, I., Shimoni, E. and Bianco-Peled, H. (2009). Studying different dimensions of amylose-long chain fatty acid complexes: molecular, nano and micro level characteristics. Food hydrocolloids, 23, 7, 1918-1925.
  60. Lesmes, U., Sner, Y., Cohen, S., and Shimoni E. (2009). Effects of long chain fatty acid unsaturation on the structure and controlled release properties of amylose complexes, Food Hydrocolloids, 23, 3, 667-675.
  61. Lesmes, U., Barchechath, J. and Shimoni, E. (2008). Continuous dual feed homogenization for the production of starch inclusion complexes for controlled release of nutrients, Innovative Food Science and Emerging Technologies, 9, 4, 507-515.
  62. Lesmes, U., Breads, E. J., Gibson, G. R., Tuohy, K. M. and Shimoni, E. (2008). Effects of Resistant Starch Type III Polymorphs on Human Colon Microbiota and Short Chain Fatty Acids in Human Gut Models, Journal of Agricultural and Food Chemistry, 56, 13, 5415–5421.
PROFESSIONAL PEER-REVIEWED REVIEW/OPINION PAPERS
  1. Mashiah, L., Medini, O., Araiza Calahorra, A., Skaret, J., Shani Levi, C., Egger, L., Portmann, R., Varela, P., Sarkar, A. and Lesmes, U. (2025). Strategic considerations in designing food solutions for seniors, Foods, 14(3), 396.
  2. Lesmes, U. (2023). In vitro digestion models in the design of safe and nutritious foods. Advances in Food and Nutrition Research, 104:179-203.
  3. Meshulam-Pascoviche, D., David-Birman, T., Rafael, G. and Lesmes, U. (2022). Big opportunities for tiny bugs: Processing effects on the techno-functionality and digestibility of edible insects. Trends in Food Science and Technology, 122, 265-274.
  4. Lesmes, U. (2020). Editorial overview: Food chemistry and biochemistry Vol. 31 (Current status in our understanding of physicochemical basis of bioaccessibility). Current Opinion in Food Science, 31, Pages iii-iv.
  5. David, S., Fahoum, L., Rozen, G., Shaoul, R., Shpigelman, A., Meyron-Holtz, E.G. and Lesmes, U. (2019). Reply to the Comment on “Revisiting the carrageenan controversy: do we really understand the digestive fate and safety of carrageenan in our foods?” by M. Weiner and J. McKim, Food Funct., 2019, 10: DOI: 10.1039/C8FO01282B. Food and Function, 10, 1763.
  6. David, S., Fahoum, L., Rozen, G., Shaoul, R., Shpigelman, A., Meyron-Holtz, E.G. and Lesmes, U. Reply to the Comment on “Revisiting the carrageenan controversy: do we really understand the digestive fate and safety of carrageenan in our foods?” by M. Weiner and J. McKim, DOI: 10.1039/C8FO01282B.  (2019).Food and Function, 10, 1763–1766.
  7. David, S., Shani Levi, C., Fahoum, L., Meyron-Holtz, E.G., Shpigelman, A. and Lesmes, U., (2018). Revisiting the carrageenan controversy: do we really understand the digestive fate and safety of carrageenan in our foods?. Food and Function, 9, 1344-1352.
  8. T. Bohn, F. Carriere, L. Day, A. Deglaire, L. Egger, D. Freitas, M. Golding, S. Le Feunteun, A. Macierzanka, O. Menard, B. Miralles, A. Moscovici, R. Portmann, I. Recio, D. Rémond, V. Santé-Lhoutelier, T.J. Wooster, U. Lesmes, A.R. Mackie & D. Dupont (2017). Correlation between in vitro and in vivo data on food digestion. What can we predict with static in vitro digestion models?, Critical Reviews in Food Science and Nutrition, Accepted – In Press, http://dx.doi.org/10.1080/10408398.2017.1315362.
  9. Shani Levi, C., Alvito, P., Andrés, A., Assunção, R., Barberá, R., Blanquet-Diot, S., Bourlieu, C., Brodkorb, A., Cilla, A., Deglaire, A., Denis, S., Dupont, D., Heredia, A., Karakaya, S., Lucia Giosafatto, C.V., Mariniello, L., Martins, C., Ménard, O., Nehir El, S., Vegarud, G.E., Ulleberg E. and Lesmes, U., Extending in vitro digestion models to specific human populations: Perspectives, practical tools and bio-relevant information, Trends in Food Science and Technology, Accepted – In Press, On-line November, 9, 2016.
  10. Benshitrit, R., Shani Levi, C., Tal Levi, S., Shimoni, E. and Lesmes, U. (2012).  Development of oral food-grade delivery systems: current knowledge and future challenges. Food and Function, 3, 10-21. Selected as cover article.
  11. Normand, M.D., Lesmes, U., Corradini, M. G. and Peleg, M. (2010). Free Interactive Software for Food Engineering Education and Practice, Food Engineering Reviews, 2, 157–167.
  12. Lesmes, U. and McClements, D. J. (2009). Structure-Function Relationships to Guide Rational Design and Fabrication of Particulate Food Delivery Systems. Trends in food science & technology, 20, 10, 448-457.
BOOK CHAPTERS AND OTHER PUBLICATIONS
  1. Lemses, U. Quantifying Digestion Products: Physicochemical Aspects. In “Interdisciplinary Approaches to Food Digestion” (2019). Gouseti, O. Ed. Springer Nature publishing.
  2. Lesmes, U. From creeps to chips: Smart design of novel food sources towards tailored digestibility and personalization. (2018) World Food Day 2018: Special issue on Food Tech, AgriIsrael- Israeli Agriculture International portal.
  3. Elad, A.M. and Lemses, U. Nutritional Programming of Probiotics to Promote Health and Well Being. In “Probiotics” (2012). Edited by Rigobelo, E. InTech – open science on-line publishing.Lemses, U. Prebiotics – modulators of the human gut microflora. In “Beneficial Microorganisms in Multicellular Life Forms” (2011). Rosenberg, E. and Gophna U. Eds. Springer publishing.
  4. Normand, M.D., Lesmes, U. and McClements, D.J. (2010). Model for the formulation of multilayered emulsions. Free Interactive demonstration, Wolfram Demonstrations Project.